Research Associate. ImmVar Project, Department of Pathology, Harvard
Medical School.
The ImmVar Project is a collaborative consortium of
immunologists, geneticists and computational biologists that seeks to elucidate
the impact of genetic variation on genomic activity in immune cells. The
program, based at Harvard Medical School, the Broad Institute and Stanford
University, will generate genome-wide gene expression profiles (mRNA and miRNA) of
purified immunocytes from a large cohort of individuals across population and
age groups, at baseline and in response to immune triggers. These data will
serve to support computational analyses of genetic regulatory networks.
Responsibilities:
The Research Associate will play a central role in the project. Under the
overall direction of project Principal Investigators, will be responsible for
orchestrating, and participating in if needed, the various arms of the project: identification and recruitment of sample donors,
the processing of samples through flow cytometry and cell culture, and the generation
of SNP and expression data from microarray, Nanostring or like technologies.
Will be collaboratively involved in analysis of the expression and genetic
data, in relation with computational biologists in the project. Will serve as
the primary contact point between project leaders, staff, and collaborators to
address all issues relating to the project, coordinating input between the
project’s various sites. Will assist with the submission of IRB, NIH and other
required documentation or reporting required for the project. Will plan and
participate in project-wide meetings and discussion groups, represent the
project both externally and internally. Will participate in elaboration of data
dissemination, through conventional publications as well as via dedicated
web-based structures designed by the project’s software engineers.
Basic Qualifications: PhD in Molecular Biology or similar discipline,
with at least 3 years post-doctoral experience in a research setting in
genomics or immunology are required.
Additional Qualifications: We are looking for someone
with experience in high-throughput genetic/genomics technology, and ideally
with experience in team leadership within large projects. Experience with Human
Subjects research and IRB issues would be a plus. Candidates with the ability
to prioritize and handle a wide range of tasks simultaneously, and possess good
judgment, sense of initiative, and a detail focus will be highly regarded.
If interested, please send Letter and CV to:
Harvard University is an Affirmative Action/Equal
Opportunity Employer.
Harvard Medical School