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Senior Scientist, Formulation,...


Job Summary

Pearl River, NY
Other/Not Classified
Job Type
Full Time
Career Level
Experienced (Non-Manager)
Job Reference Code

Senior Scientist, Formulation, Vaccine R&D

About the Job

The individual is expected to independently design, develop, and execute studies to support the development of stable, robust formulations for new vaccine antigen candidates within Vaccine Research and Development.  They should define suitable processes and steps for manufacturing early formulations for both early animal studies and for formal RegTox studies. The successful candidate will have a working knowledge of what is required to scale up a process and is feasible with respect to a formulation that is suitable for clinical studies.


  • The individual should be able to, with guidance from their manager, develop and communicate a formulation development executable plan, which incorporates knowledge about the antigen (s), material availability and program timelines.
  • Design and execute targeted DS and DP formulation studies to support formulation development of vaccine antigen candidates within Vaccine Research and Development (VRD). Vet plans with management and work with the appropriate lines to secure the needed analytical characterization support.
  • Design and prepare DP formulations for early research animal studies. The formulator is expected to be able to calculate how to add the various materials to hit the targeted formulation in a consistent manner.
  • Perform relevant biophysical and particle characterization of the prepared formulations, using techniques such as micro-flow imaging (MFI), dynamic light scattering (DLS), and zeta potentials. 
  • Have the ability to analyze data coming from multiple sources and to propose formulation study conclusions that drive decisions to be made. The individual should be able to communicate the collective findings and propose follow on actions, in a clear and concise manner, as required. 
  • The individual is expected to execute assignments with limited direct supervision and have the ability to prioritize the program deliverables against other activities  The individual should be able to coordinates activities with others both inside and outside their immediate group, and should be aware of all related timelines or due dates.
  • Stay current with the scientific literature. Leverage existing knowledge appropriately, being mindful of potential patents.
  • Satisfactorily completes all cGMP/GLP and safety training in compliance with departmental requirements. Where applicable, performs job responsibilities in compliance with cGMP/GLP and all other regulatory agency requirements.
  • Complete all assigned training on time.
  • Performs other duties as assigned.


  • PhD with 0-3 years’ experience in Pharmaceutics, Biochemistry, Life Sciences or related science
  • Experience in pharmaceutical development and sterile drug product manufacturing
  • Relevant experience  in viral vaccine, protein and conjugate, or biologics formulation development
  • Experience using biophysical formulation characterization techniques such as DSC, DLS, KF, and particle sizing techniques
  • Must have good technical, organizational, and communication skills
  • Have an ability to troubleshoot issues and interpret data in the context of project needs
  • Previous experience with viral and RNA/DNA vaccines is a plus
  • Hands-on experience with liposome and lipid nanoparticle delivery system and formulation development is a plus

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.   Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Other Job Details:

  • Eligible for Relocation Package
  • Eligible for Employee Referral Bonus

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.


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