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Director, Quantitative Bioinfo...


Job Summary

Cambridge, MA
Other/Not Classified
Job Type
Full Time
Career Level
Experienced (Non-Manager)
Job Reference Code

Director, Quantitative Bioinformatics

About the Job


The leader in this role is responsible for managing the Clinical Bioinformatics group within Precision Medicine (PM) in Early Clinical Development (ECD).   The groups’ responsibilities encompass all programs in the East Coast Research Units (RUs) including Internal Medicine, Inflammation and Immunology,  Rare Disease and CTI.  Scientists in PM Clinical Bioinformatics work collaboratively across research, technical, and clinical teams to deliver computational support for high dimensional biomarker data sets for early clinical trials.  

The individual in this position is able to communicate effectively with senior leaders, lead and collaborate with colleagues within a matrix organization, and leverage technical and scientific information from a variety of sources in order to effectively  enable data analysis and drive program decisions.

The leader in this role will demonstrate the ability to build a high performance team where technical excellence, empowerment, career development and leadership at all levels is expected and fostered.  The person in this position will have a demonstrated record of developing partnerships in a matrix environment, and must have excellent interpersonal as well as oral and written communication skills.  In addition the individual must have strategic insights to enable the development and evolution of the group and its available toolkit to support the changing demands of the Pfizer portfolio.


Precision Medicine Clinical Bioinformatics Group Leadership:

  • Provides leadership to small group of Director and Senior Manager level colleagues, including responsibility for ensuring colleague training, performance management, workload management and prioritization, technical supervision, and ensuring conduct of compliance related activities of direct reports. 
  • Defines and evolves best practices across the group and partners with Research Unit, Business Technology (BT) and partner line bioinformatics experts to align approaches, develop best practices and assess and develop new technology.    
  • Responsible for ensuring high-quality data analysis is incorporated into clinical exploratory-research programs, including contributions to Exploratory Analysis Plans and summary of results, in partnership with biostatisticians and other team members.
  • Partners closely with RUs, Clinical Teams, Statistics, BT and PM functions to identify, pilot and incorporate new bioinformatics tools to support clinical trials
  • Responsible for identifying external collaborators to expand capabilities and explore new methodologies.  Responsible for establishing and maintaining external collaborations to specified timelines and milestones
  • Contribute effectively to the strategy for Precision Medicine, Big Data Analytics and application of Artificial Intelligence and Machine Learning approaches to derive insights from complex datasets.

Precision Medicine Leadership Team:

  • Core member of the ECD PM leadership team enabling cross discipline planning, colleague development and engagement. 
  • Coaches and mentors others in the organization and actively participates in development strategies to enable effective workforce and succession planning within PM.
  • Participates in and/or leads PM strategic, scientific and process initiatives to develop new or expanded capabilities in support of portfolio delivery and contributes to the development of the direction of PM.  


  • PhD or equivalent in computational biology, bioinformatics or related disciplines with minimum of 10 years of experience.
  • Able to effectively manage a diverse and dynamic workload
  • Programming skills in Java, Perl, Python or R with expertise in big data, data visualization, and web based applications.
  • Strong knowledge and understanding of statistical analytical methods that can be applied to genetics and omics data analysis.
  • Experience working with large  exploratory clinical trial datasets and strong working knowledge of high dimensional exploratory biomarker platforms (eg. transcriptomic, proteomic, metabolomics)
  • Expertise in next generation sequencing technologies and data analysis pipeline development
  • Experience in vendor interactions including managing delivery to timelines and ensuring quality deliverables
  • Demonstrated ability to develop, influence and champion bioinformatics strategies with scientific team audiences and management.  Proven record of developing effective partnerships in a matrix environment
  • A record of managerial/supervisory and leadership excellence: proven success in talent identification and development, conflict management, effective team building, strategic agility and business acumen.   
  • Excellent interpersonal and verbal and written communication skills; ability to clearly convey vision, establish strategic direction and set priorities.   Experience presenting to external multi-disciplinary scientific audiences.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.   Pfizer is an E-Verify employer.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

Other Job Details:

  • Last Date to Apply for Job: October 15, 2018
  • Eligible for Relocation Package: yes
  • Eligible for Employee Referral Bonus: yes

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.


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