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What type of mark will you make?

Your unique talents and perspective can make a vital contribution to innovative products that improve the lives of people everywhere. Career opportunities within Johnson & Johnson companies can provide a setting to build your leadership experience, express your passion, and touch the world.

Position Description


Johnson & Johnson companies are equal opportunity employers.



Janssen Pharmaceuticals, Inc, a member of Johnson & Johnson's Family of Companies, is recruiting for a Principal Scientist, PET Pharmacology, to be located in La Jolla, CA.

Janssen Pharmaceutical Companies of Johnson & Johnson are dedicated to addressing and solving the most important unmet medical needs of our time, including in oncology, immunology, neuroscience, infectious disease, and cardiovascular and metabolic diseases. Driven by our commitment to patients, we develop sustainable, integrated healthcare solutions by working side-by-side with healthcare stakeholders, based on partnerships of trust and transparency.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

The PET Pharmacology Principal Scientist will be a member of the Neuroscience Biomarkers team, and will be responsible for conducting collaborative imaging biomarker research with internal and external partners. This individual will conduct and manage preclinical experiments, including microPET imaging, aimed at testing and validating candidate PET tracers. S/he will manage and report project progress and time lines to the Director of the Imaging lab as well as Discovery scientists in Mood Disorders and Alzheimer’s Disease. The scientific focus for this position consists of Neuroscience imaging biomarker projects for target engagement and response measurements in Mood and AD. The operational focus for this position consists of working with PET scientists to collaboratively devise detailed molecular imaging tracer development programs and manage their execution. This individual will perform in-house microPET imaging. S/he will interface with internal and external resources for the generation and analysis of in vivo data. S/he will study target engagement, metabolism, biodistribution and clearance kinetics. S/he will devise experiment for conducting safety assessment.

The Principal Scientist PET Pharmacology, will also interface with internal and external scientific experts. S/he will interact internally with PET tracer scientists, NS Mood and AD Discovery Scientists, Discovery Sciences, Experimental Medicine, purchasing, and contracting. S/he will interact externally with Academics or CRO’s for preclinical imagining.


A minimum of a Ph.D. degree in Pharmacology or Biology is required. A minimum of 5-8 years of related experience (preclinical PET imaging) is required. On-the-job experience with imaging biomarker development and hands-on experience in preclinical PET imaging is required. Hands-on experience with candidate tracer testing in rodent models is required. Strong communication skills are required. Strong collaboration and influencing skills are required. The position is located in La Jolla, CA and may require <10% travel.

BE VITAL in your career, Be seen for the talent you bring to work. Explore opportunities within the Johnson & Johnson Family of Companies.


Primary Location:North America-United States-California-San Diego
Organization: Janssen Research & Development, LLC. (6084)
Job Function: Pharmacokinetics

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Johnson and Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, protected veteran status, or disability status, or any other characteristic protected by law.

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